Applications of large language models in depression treatment: a systematic review

Authors

  • Maurício Rodrigues Lima UFG
  • Deller James Ferreira UFG
  • Elisângela Silva Dias UFG

DOI:

https://doi.org/10.59681/2175-4411.v16.iEspecial.2024.1318

Keywords:

Mental Health, Depression, Large Language Models

Abstract

Objective: This study reviews the use of Large Language Models (LLMs) in the field of mental health, specifically focusing on the treatment of depression. Method: A total of 18 articles out of an initial 121 were analyzed, exploring how LLMs assist in clinical decision- making and interaction between mental health professionals and depressed patients. Results: The main findings show that LLMs can increase accuracy in detecting symptoms and enhance therapeutic interventions through advanced conversational interfaces. Conclusion: The summary highlights gaps in existing research and emphasizes the study's contribution to a better understanding of the applicability of LLMs in clinical contexts. 

Author Biographies

Maurício Rodrigues Lima, UFG

Especialista em Engenharia de Software, Instituto de Informática, UFG, Goiânia (GO), Brasil.

Deller James Ferreira, UFG

Professora Dra, Instituto de Informática, UFG, Goiânia (GO), Brasil.

Elisângela Silva Dias, UFG

Professora Dra, Instituto de Informática, UFG, Goiânia (GO), Brasil.

References

Liu S, Zheng C, Demasi O, Sabour S, Li Y, Yu Z, Jiang Y, Huang M. Towards Emotional Support Dialog Systems. In: Zong C, Xia F, Li W, Navigli R, editors. Proceedings of the 59th Annual Meeting of the Association for Computational Linguistics and the 11th International Joint Conference on Natural Language Processing (Volume 1: Long Papers); 2021 Aug; Online. Association for Computational Linguistics; p. 3469–3483. Disponível em: https://aclanthology.org/2021.acl-long.269. DOI: 10.18653/v1/2021.acl-long.269. DOI: https://doi.org/10.18653/v1/2021.acl-long.269

Grové C. Co-developing a mental health and wellbeing chatbot with and for young people. Frontiers in Psychiatry. 2021;11. DOI: https://doi.org/10.3389/fpsyt.2020.606041

Demszky D, et al. Using large language models in psychology. Nature Reviews Psychology. 2023;2(11):688–701. DOI: https://doi.org/10.1038/s44159-023-00241-5

Siddaway AP, Wood A, Hedges L. How to do a systematic review: A best practice guide for conducting and reporting narrative reviews, meta-analyses, and meta-syntheses. Annual Review of Psychology. 2019;70:747-770. DOI: 10.1146/annurev-psych-010418-102803. DOI: https://doi.org/10.1146/annurev-psych-010418-102803

Carrera-Rivera A, et al. How-to conduct a systematic literature review: A quick guide for computer science research. MethodsX. 2022;9:101895. DOI: https://doi.org/10.1016/j.mex.2022.101895

Page M, et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. Journal of Clinical Epidemiology. 2021.

Hwang G, et al. Assessing the potential of chatgpt for psychodynamic formulations in psychiatry: An exploratory study. Psychiatry Research. 2024;331:115655. DOI: https://doi.org/10.1016/j.psychres.2023.115655

Furukawa TA, et al. Harnessing AI to optimize thought records and facilitate cognitive restructuring in smartphone CBT: An exploratory study. Cognitive Therapy and Research. 2023;47(6):887–893. DOI: https://doi.org/10.1007/s10608-023-10411-7

Bucur A-M. Utilizing chatgpt generated data to retrieve depression symptoms from social media. 2023. DOI: https://doi.org/10.1007/978-3-031-71736-9_14

Hashem R, et al. AI to the rescue: Exploring the potential of chatgpt as a teacher ally for workload relief and burnout prevention. Research and Practice in Technology Enhanced Learning. 2024;19:023. DOI: https://doi.org/10.58459/rptel.2024.19023

Gabor-Siatkowska K, et al. AI to train AI: Using chatgpt to improve the accuracy of a therapeutic dialogue system. Electronics. 2023;12(22). DOI: https://doi.org/10.3390/electronics12224694

Levkovich I, Elyoseph Z. Identifying depression and its determinants upon initiating treatment: Chatgpt versus primary care physicians. Family Medicine and Community Health. 2023;11(4). DOI: https://doi.org/10.1136/fmch-2023-002391

Montag C, et al. On artificial intelligence and global mental health. Asian Journal of Psychiatry. 2023;103855. DOI: https://doi.org/10.1016/j.ajp.2023.103855

Dougherty RF, et al. Psilocybin therapy for treatment resistant depression: prediction of clinical outcome by natural language processing. Psychopharmacology. 2023. DOI: https://doi.org/10.1007/s00213-023-06432-5

Bird JJ, Lotfi A. Generative transformer chatbots for mental health support: A study on depression and anxiety. In: Proceedings of the 16th International Conference on PErvasive Technologies Related to Assistive Environments, PETRA ’23; 2023 p. 475–479. New York, NY, USA: Association for Computing Machinery. DOI: https://doi.org/10.1145/3594806.3596520

Brooks JA, et al. Emotion expression estimates to measure and improve multimodal social-affective interactions. In: Companion Publication of the 25th International Conference on Multimodal Interaction, ICMI ’23 Companion; 2023 p. 353–358. New York, NY, USA: Association for Computing Machinery. DOI: https://doi.org/10.1145/3610661.3616129

Bokolo Biodoumoye George, Liu Qingzhong. Deep Learning-Based Depression Detection from Social Media: Comparative Evaluation of ML and Transformer Techniques. Electronics. 2023;12(21):4396. Disponível em: https://www.mdpi.com/2079-9292/12/21/4396. DOI: 10.3390/electronics12214396. DOI: https://doi.org/10.3390/electronics12214396

Zhou W, et al. Identifying rare circumstances preceding female firearm suicides: Validating a large language model approach. JMIR Ment Health. 2023;10. DOI: https://doi.org/10.2196/49359

Published

2024-11-19

How to Cite

Lima, M. R., Ferreira, D. J., & Dias, E. S. (2024). Applications of large language models in depression treatment: a systematic review. Journal of Health Informatics, 16(Especial). https://doi.org/10.59681/2175-4411.v16.iEspecial.2024.1318

Similar Articles

<< < 7 8 9 10 11 12 13 14 15 16 > >> 

You may also start an advanced similarity search for this article.