Artificial intelligence for cataract diagnosis and referral using real-world database

Authors

DOI:

https://doi.org/10.59681/2175-4411.v17.2025.1441

Keywords:

Artificial Intelligence, Diagnosis, Cataract

Abstract

The use of artificial intelligence (AI) for ophthalmology applications has shown g promising results worldwide; however, its performance is dependent on population groups and must be evaluated in real-world scenarios. We evaluated the use of AI for cataract diagnosis and referral to specialists using a real-world database consisting of 2642 eye images from a working telemedicine service in South Brazil. Our AI solution adopts an ensemble model to improve classifier performance. The best results showed an accuracy of 90.6% for cataract diagnosis with a corresponding area under the receiver operating characteristic curve (ROC AUC) of 96.7%. The accuracy for surgical referral was 86.5% with a corresponding ROC AUC of 94.3%. The results indicate that the use of an ensemble of models and training with a heterogeneous real-world clinical database enabled our solution to achieve superior performance compared to other works in the literature when evaluated on real-world data.

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Author Biographies

Marcelo Negreiros, Universidade Federal do Rio Grande do Sul

Researcher at SENAI Innovation Institute for Sensing Systems (ISI-SIM), São Leopoldo, Brazil. He was an associated researcher at UFRGS, Porto Alegre, Brazil, during the development of this work.

Ronaldo Husemann, Universidade Federal do Rio Grande do Sul

Adjunct professor at Electrical Engineering Department at UFRGS, Porto Alegre, Brazil.

Valter Roesler, Universidade Federal do Rio Grande do Sul

Associated professor at Informatics Institute at UFRGS, Brazil.

Aline L. de Araujo, Universidade Federal do Rio Grande do Sul

Researcher at Teleoftalmo Telessaúde RS-UFRGS, Brazil.

Dimitris Rucks Varvaki Rados , Universidade Federal do Rio Grande do Sul

Professor of Internal Medicine at UFRGS, Brazil.

Felipe C. Cabral, Hospital Moinhos de Vento

Researcher at Hospital Moinhos de Vento, Rio Grande do Sul, Brazil.

Natan Katz , Universidade Federal do Rio Grande do Sul

Professor of Family Medicine at UFRGS.

References

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Fotografia mostra médica oftalmologista examinando uma paciente. Fotografia cedida pelo Hospital Moinhos de Vento.

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Published

2025-10-31

How to Cite

Negreiros, M., Husemann, R., Roesler, V., Araujo, A. L. de, Rados , D. R. V., Cabral, F. C., & Katz , N. (2025). Artificial intelligence for cataract diagnosis and referral using real-world database. Journal of Health Informatics, 17(1), 1441. https://doi.org/10.59681/2175-4411.v17.2025.1441

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